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Research Article 


The Efficacy of Mesenchymal Stem Cells loaded in Acacia Gum Hydrogel and Acacia Gum Hydrogel on Skin Wounds Healing in Rats

Wissam Abdullah Alhayani.


Abstract
Cutaneous wound healing processes start at the beginning of the trauma leading to impairment of physical and functional tissue continuity. The present work aimed to clarify the efficacy of stem cells loaded in acacia gum hydrogel and acacia gum hydrogel on skin wound healing in rats. Thirty-six adult male rats (Wister rats). The weight of the rats was estimated between 150-160 grams and the animals were divided into three groups (n=12). In Group A (control group), the surgical skin wound was established and treated with normal saline only. Group B: surgical skin wound was made and covered with Acacia gum hydrogel. Group C: surgical skin wound was made and covered with mesenchymal stem cells loaded in Acacia gum hydrogel. Examination of wound healing on days 3, 7, 14 and 21 for gross and microscopic pathological changes. The gross pathological evaluation showed no significant difference between all groups but the histopathological result showed the Acacia gum improved wound recovery better than the control group, although the wound was not completely closed on day 21 in Acacia gum and control groups contrary to the stem cells treated group, which showed complete wound closure. The best ever histopathological result of wounds healing in mesenchymal stem cells loaded in acacia gum hydrogel treated groups.


 
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How to Cite this Article
Pubmed Style

Wissam Abdullah Alhayani. The Efficacy of Mesenchymal Stem Cells loaded in Acacia Gum Hydrogel and Acacia Gum Hydrogel on Skin Wounds Healing in Rats. AJVS. 2022; 15(1): 58-65. doi:10.37940/AJVS.2021.15.1.8

Web Style

Wissam Abdullah Alhayani. The Efficacy of Mesenchymal Stem Cells loaded in Acacia Gum Hydrogel and Acacia Gum Hydrogel on Skin Wounds Healing in Rats. https://www.anbarjvs.edu.iq/?mno=302657448 [Access: December 14, 2024]. doi:10.37940/AJVS.2021.15.1.8

AMA (American Medical Association) Style

Wissam Abdullah Alhayani. The Efficacy of Mesenchymal Stem Cells loaded in Acacia Gum Hydrogel and Acacia Gum Hydrogel on Skin Wounds Healing in Rats. AJVS. 2022; 15(1): 58-65. doi:10.37940/AJVS.2021.15.1.8


Vancouver/ICMJE Style

Wissam Abdullah Alhayani. The Efficacy of Mesenchymal Stem Cells loaded in Acacia Gum Hydrogel and Acacia Gum Hydrogel on Skin Wounds Healing in Rats. AJVS. (2022), [cited December 14, 2024]; 15(1): 58-65. doi:10.37940/AJVS.2021.15.1.8


Harvard Style

Wissam Abdullah Alhayani (2022) The Efficacy of Mesenchymal Stem Cells loaded in Acacia Gum Hydrogel and Acacia Gum Hydrogel on Skin Wounds Healing in Rats. AJVS, 15 (1), 58-65. doi:10.37940/AJVS.2021.15.1.8


Turabian Style

Wissam Abdullah Alhayani. 2022. The Efficacy of Mesenchymal Stem Cells loaded in Acacia Gum Hydrogel and Acacia Gum Hydrogel on Skin Wounds Healing in Rats. Al-Anbar Journal of Veterinary Sciences, 15 (1), 58-65. doi:10.37940/AJVS.2021.15.1.8


Chicago Style

Wissam Abdullah Alhayani. "The Efficacy of Mesenchymal Stem Cells loaded in Acacia Gum Hydrogel and Acacia Gum Hydrogel on Skin Wounds Healing in Rats." Al-Anbar Journal of Veterinary Sciences 15 (2022), 58-65. doi:10.37940/AJVS.2021.15.1.8


MLA (The Modern Language Association) Style

Wissam Abdullah Alhayani. "The Efficacy of Mesenchymal Stem Cells loaded in Acacia Gum Hydrogel and Acacia Gum Hydrogel on Skin Wounds Healing in Rats." Al-Anbar Journal of Veterinary Sciences 15.1 (2022), 58-65. Print. doi:10.37940/AJVS.2021.15.1.8


APA (American Psychological Association) Style

Wissam Abdullah Alhayani (2022) The Efficacy of Mesenchymal Stem Cells loaded in Acacia Gum Hydrogel and Acacia Gum Hydrogel on Skin Wounds Healing in Rats. Al-Anbar Journal of Veterinary Sciences, 15 (1), 58-65. doi:10.37940/AJVS.2021.15.1.8


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