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Research Article

Online Publishing Date:
30 / 06 / 2020

 


The Effect of Diabetes on the Physiological Parameters in Male Rats

Ziadoon fawzi mukhlif, Saleh M Rahim, Mustafa nuhad jumaa jamal.


Abstract
The aim of this study is to assess the effects of high blood glucose levels in male rats with diabetes induced by alloxan on their physiological conditions. Diabetes mellitus is a category of metabolic hyperglycemia disorders caused by insufficient body production or pancreatic action. In addition to hyperglycemia, a number of other factors are also important for pathogenesis, such as Hyperlipidemics and cortisol oxidative. Forty-five mature male rats were used in this study, these were divided into 3 groups, Control group(G1) : gavage distilled water, Group2(G2): injection intraperitoneally with Alloxan150 mg/kg bw for two weeks, and Group3(G3): injection intraperitoneally with Alloxan 150mg/kg bw for twenty-four days. Blood samples taken from all groups estimation of Peroxynitrite, GSH, CAT, and SOD concentrations%. The findings revealed a significant improvement in diabetic classes in glucose (p<0.05) and peroxynitrite relative to control (G1). Diabetic concentrations of (G2, G3) relative to the control group (G1) were substantially reduced in SOD, GSH, CAT, and diabetes-mediated (P < 0,05). In conclusion, diabetes can cause significant changes in SOD, GSH, and CAT levels in rats.

Key words: Rats, Diabetes, Physiological parameters, SOD, GSH and CAT


 
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How to Cite this Article
Pubmed Style

mukhlif Zf, Rahim SM, jamal Mnj. The Effect of Diabetes on the Physiological Parameters in Male Rats. AJVS. 2020; 13(1): 66-73. doi:https//doi.org/10.37940/AJVS.2020.13.1.8

Web Style

mukhlif Zf, Rahim SM, jamal Mnj. The Effect of Diabetes on the Physiological Parameters in Male Rats. https://www.anbarjvs.edu.iq/?mno=114715 [Access: June 16, 2024]. doi:https//doi.org/10.37940/AJVS.2020.13.1.8

AMA (American Medical Association) Style

mukhlif Zf, Rahim SM, jamal Mnj. The Effect of Diabetes on the Physiological Parameters in Male Rats. AJVS. 2020; 13(1): 66-73. doi:https//doi.org/10.37940/AJVS.2020.13.1.8


Vancouver/ICMJE Style

mukhlif Zf, Rahim SM, jamal Mnj. The Effect of Diabetes on the Physiological Parameters in Male Rats. AJVS. (2020), [cited June 16, 2024]; 13(1): 66-73. doi:https//doi.org/10.37940/AJVS.2020.13.1.8


Harvard Style

mukhlif, Z. f., Rahim, . S. M. & jamal, . M. n. j. (2020) The Effect of Diabetes on the Physiological Parameters in Male Rats. AJVS, 13 (1), 66-73. doi:https//doi.org/10.37940/AJVS.2020.13.1.8


Turabian Style

mukhlif, Ziadoon fawzi, Saleh M Rahim, and Mustafa nuhad jumaa jamal. 2020. The Effect of Diabetes on the Physiological Parameters in Male Rats. Al-Anbar Journal of Veterinary Sciences, 13 (1), 66-73. doi:https//doi.org/10.37940/AJVS.2020.13.1.8


Chicago Style

mukhlif, Ziadoon fawzi, Saleh M Rahim, and Mustafa nuhad jumaa jamal. "The Effect of Diabetes on the Physiological Parameters in Male Rats." Al-Anbar Journal of Veterinary Sciences 13 (2020), 66-73. doi:https//doi.org/10.37940/AJVS.2020.13.1.8


MLA (The Modern Language Association) Style

mukhlif, Ziadoon fawzi, Saleh M Rahim, and Mustafa nuhad jumaa jamal. "The Effect of Diabetes on the Physiological Parameters in Male Rats." Al-Anbar Journal of Veterinary Sciences 13.1 (2020), 66-73. Print. doi:https//doi.org/10.37940/AJVS.2020.13.1.8


APA (American Psychological Association) Style

mukhlif, Z. f., Rahim, . S. M. & jamal, . M. n. j. (2020) The Effect of Diabetes on the Physiological Parameters in Male Rats. Al-Anbar Journal of Veterinary Sciences, 13 (1), 66-73. doi:https//doi.org/10.37940/AJVS.2020.13.1.8


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